The big question, is it worth sticking with one airline to accumulate points, or just go for whoever has the better price?
I have Qantas and Qatar, Singapore, Etihad and Emirates points. The first four only a few, but with Emirates I have three lots of business class and if I rebook with them, even more. Although I really like Emirates does it make sense just to book with them if a better price is available.
Sorry if it's a silly question, but I don't really understand these things.
Personally I would seek the best price unless I was specifically saving up points for something like a free business class flight.
The points are usually worth 2c or less so I expect a cheaper flight would always win out.