The dosages for each weight range contain double the active ingredients, e.g. small has 18.8mg of afoxolaner, medium had 37.5mg, large had 75mg.
A pack of 6 medium costs ~$80 when a pack of 6 large cost $90.
Could I theoretically buy the large size for my medium dog and cut the chews in half and save a significant cost per month?
https://www.petcircle.com.au/discover/can-you-split-parasite…
https://www.ticknflea.com/wp-content/uploads/2020/07/nexgard…
Seems not. Check with your vet.