For about the next 2 weeks there is 30 to 50% off various Stardock games. I haven't played any of them (too busy; I purchased WindowsBlinds from them 18 months ago when I switched to Win 7 as my main OS - a great program if you take the time to acquire a set of skins you admire).
Some of the specials I recommend are: Galactic Civilizations II: Ultimate $13.39
Fallen Enchantress $26
Sins Trinity $10
If you are after "Murder Simulators", there won't be much to appeal to you here. Merry Christmas everyone!
Keep an eye on the current Steam sale. The last Steam Autumn Sale beat Stardock's sales prices for Stardock's games on Steam.