Cenovis Vitamin C 250mg - Chewable Tablets - 150 Tab $5.95 + Delivery ($0 with Prime/ $39 Spend) @ Amazon AU

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Dalton on 12/05/2023 - 12:34 amazon.com.au (249 clicks)

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If you want a lower dose chewable vitamin C tablet, this might be for you.

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  easternculture on 12/05/2023 - 12:39

  +2

  Ive been taking 1000mg daily since 4 months and have noticed my general well being and immune system has improved

  • 

    kiriakoz on 12/05/2023 - 12:51

    which ones do you take out of interest?

    • 

      Clear on 12/05/2023 - 13:04

      +1

      There was the 500mg version in a previous deal. Just take 4 of these.

      • 

        easternculture on 12/05/2023 - 13:11

        +1

        The effervescent ones at coles.
        Got them on sale for $1 each. Bought 10 of them
        20tabs @ 1000mg each and they taste nice

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  troubadour on 12/05/2023 - 14:28

  +1

  Not sure as a frugal ozbargainer I would go for "just in case" supplements. All you need is 45mg/day which should be already in your food?

  • https://www.healthdirect.gov.au/vitamin-c-and-your-health
  • https://ods.od.nih.gov/factsheets/VitaminC-HealthProfessiona…
  • 

    ozbking on 12/05/2023 - 22:06

    Not if you’re an elite skier or ultra marathon runner. These are the only two groups shown in studies to benefit from vitamin C supplementation. 200 mg a day seems to halve the incidence of colds.

    • 

      easternculture on 13/05/2023 - 13:39

      Ive observed that.
      I usually get a bad flu around feb and this time of the year
      Got nothing in feb
      Got a mild flu in late april but was literaly not noticable while my wife and kids had a cough and runny nose.
      I also noticed that im less sore and recovery time is faster post workout. If its the vit C, then i would theorise its due to its anti-inflamatory effect.

      So im going to continue high does vit C

• 

  easternculture on 13/05/2023 - 13:49

  3.4. The effect of vitamin C on immune cells activity and cytokines production
  The role of vitamin C as a modulator of immune response is well documented. It has been shown that vitamin C can modulate multiple immune cells functions and therefore might exert beneficial effects in the context of cellular immunotherapy. In vitro and in vivo studies reported that vitamin C promotes regulatory T cells (Tregs) functions through TET-dependent demethylation of the fork headbox P3 (FoxP3) regulatory elements [66], [67]. Thus, the induction and activation of TET enzymes in Tregs by vitamin C might be an attractive method for Tregs-mediated adoptive immunotherapy. It has also been shown that vitamin C increases in vivo and in vitro the proliferative capacity of human natural killer (NK) cells [68]. Interestingly, a recent study has demonstrated that vitamin C enhances the activation and differentiation of human Vγ9Vδ2 γδ T cells [69]. Therefore, vitamin C treatment can be considered as a novel strategy to optimize the in vitro generation of effective NK and Vγ9Vδ2 T cells for adoptive transfer for cancer patients. Moreover, vitamin C was shown to stimulate dendritic cells (DCs) to secrete more interleukin-12 (IL-12) and thereby drive naïve CD4 + T cells to differentiate into T helper 1 cells (Th1) [70]. Finally, treatment of mouse bone marrow-derived DCs with vitamin C led to an enhanced CD8 + memory T cell production in vivo [71].