So I can't decide should I get a:
MSI GTX 1060 6GB for $404 or;
MSI AMD 480 4GB for $337
I only game at 1080p and want the MSI Gaming X version as I want my PC to be quiet as possible, and as far as I can tell that is the quietest one available got either card.
As far as I know the 1060 is better generally but not sure it is worth 20% more.
(Prices as per MSY deal)
Short answer - yes the 1060 6GB is worth 20% more.
Apart from having sufficient headroom to handle more graphically intense games in the future, the 1060 is a more efficient design that uses less power and creates less heat - both very good things for the long-term performance of your PC. It's probably the best value GPU currently on the market, from a FPS per $ perspective.
The only reason I'd consider the 480 is if a particular game I was planning to play had significantly better DX12 performance.